Miliary tuberculosis presenting with multifocal oral lesions.

Although the method of exposure was different, the absence of reaction to the gaseous Freons suggests that they were not the component responsible for the reactions to the aerosol propellant. The only other agents to which exposure may have occurred were the aluminium can and a range of extractives from rubber components of the metering valve. There is no direct evidence that the asthmatic reactions were of an allergic nature, and some form of non-specific bronchial irritation seems a possible explanation. Such reactions to the aerosol vehicle may be obscured when it is being used for bronchodilator drugs that are effective. Investigation of adverse reactions of the sort described are indicated in patients presenting with such a history and possibly also in patients who fail to respond or who respond poorly to aerosol bronchodilators.